Consolidated Statements of Operations - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | 12 Months Ended | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dec. 31, 2018 |
Sep. 30, 2018 |
Jun. 30, 2018 |
Mar. 31, 2018 |
Dec. 31, 2017 |
Sep. 30, 2017 |
Jun. 30, 2017 |
Mar. 31, 2017 |
Jun. 30, 2018 |
Dec. 31, 2018 |
Dec. 31, 2017 |
Dec. 31, 2016 |
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| Income Statement [Abstract] | ||||||||||||
| Product sales | $ 1,071 | $ 1,169 | $ 483 | $ 1,726 | $ 896 | $ 589 | $ 603 | $ 0 | $ 4,449 | $ 2,088 | $ 0 | |
| Operating Expenses [Abstract] | ||||||||||||
| Cost of product sales | 6,272 | 6,453 | 4,600 | 5,436 | 3,870 | 3,140 | 2,531 | 0 | 22,761 | 9,541 | 0 | |
| Research and development cost | 857 | 967 | 1,203 | 1,475 | 1,565 | 1,367 | 2,184 | 2,987 | 4,502 | 8,103 | 6,348 | |
| General and administrative expense | 6,352 | 2,174 | 3,913 | 1,775 | 1,994 | 1,925 | 1,444 | 1,528 | $ 400 | 14,214 | 6,891 | 6,610 |
| Impairment charge | 0 | 0 | 2,411 | 0 | 2,411 | 0 | ||||||
| Total operating expense | 13,481 | 9,594 | 9,716 | 8,686 | 7,429 | 6,432 | 8,570 | 4,515 | 41,477 | 26,946 | 12,958 | |
| Loss from operations | (12,410) | (8,425) | (9,233) | (6,960) | (6,533) | (5,843) | (7,967) | (4,515) | (37,028) | (24,858) | (12,958) | |
| Nonoperating Income (Expense) [Abstract] | ||||||||||||
| Interest expense | (1,222) | (919) | (719) | (587) | (511) | (454) | (408) | (388) | (3,447) | (1,761) | (639) | |
| Interest and other income | 100 | 81 | 25 | 17 | 13 | 7 | 10 | 11 | 223 | 41 | 41 | |
| Total other expense, net | (1,122) | (838) | (694) | (570) | (498) | (447) | (398) | (377) | (3,224) | (1,720) | (598) | |
| Loss before income tax expense | (13,532) | (9,263) | (9,927) | (7,530) | (7,031) | (6,290) | (8,365) | (4,892) | (40,252) | (26,578) | (13,556) | |
| Income tax expense | 0 | 0 | 0 | (2) | 0 | 0 | 0 | (2) | (2) | (2) | (1) | |
| Net loss | $ (13,532) | $ (9,263) | $ (9,927) | $ (7,532) | $ (7,031) | $ (6,290) | $ (8,365) | $ (4,894) | $ (40,254) | $ (26,580) | $ (13,557) | |
| Weighted average shares outstanding, basic and diluted (in shares) | 38,905,282 | 38,779,710 | 30,134,995 | 27,768,008 | 21,956,993 | 20,265,020 | 20,123,041 | 18,792,850 | 34,154,826 | 20,293,100 | 15,267,233 | |
| Basic and diluted net loss per share (in dollars per share) | $ (0.35) | $ (0.24) | $ (0.33) | $ (0.27) | $ (0.32) | $ (0.31) | $ (0.42) | $ (0.26) | $ (1.18) | $ (1.31) | $ (0.89) | |
| X | ||||||||||
- Definition The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. No definition available.
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The amount of impairment loss recognized in the period resulting from the write-down of the carrying amount of a finite-lived intangible asset to fair value. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The amount of interest income and other income recognized during the period. Included in this element is interest derived from investments in debt securities, cash and cash equivalents, and other investments which reflect the time value of money or transactions in which the payments are for the use or forbearance of money and other income from ancillary business-related activities (that is, excluding major activities considered part of the normal operations of the business). No definition available.
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- Definition Amount of the cost of borrowed funds accounted for as interest expense. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business). Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. No definition available.
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- References No definition available.
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- Definition The net result for the period of deducting operating expenses from operating revenues. No definition available.
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- Definition The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS). No definition available.
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