Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity (Details 2)

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Stockholders' Equity (Details 2) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Stock-based compensation expense $ 125 $ 160 $ 592 $ 898
Cost of Product Sales [Member]        
Stock-based compensation expense 17 41
Research and Development Cost [Member]        
Stock-based compensation expense 62 120 222 226
General and Administrative Expense [Member]        
Stock-based compensation expense $ 46 $ 40 $ 329 $ 672