Supplemental Financial Information (Tables)

12 Months Ended

Dec. 31, 2017

Unaudited Quarterly Results of Operations

(in thousands, except share and per share amounts)

	Three months ended
	March 31,			June 30,			September 30,			December 31,			Total for year
	2017			2017			2017			2017			2017

Revenue - sales	$	—		$	603		$	589		$	896		$	2,088

Operating expenses
Cost of product sales		—			2,531			3,140			3,870			9,541
Operations and development costs		2,987			2,184			1,367			1,565			8,103
General and administrative expense		1,528			1,444			1,925			1,994			6,891
Impairment charge					2,411			—			—			2,411
Total operating expenses		4,515			8,570			6,432			7,429			26,946
Loss from operations		(4,515	)		(7,967	)		(5,843	)		(6,533	)		(24,858	)
Other income and expense
Interest expense		(388	)		(408	)		(454	)		(511	)		(1,761	)
Interest and other income		11			10			7			13			41
Total other income (expense), net		(377	)		(398	)		(447	)		(498	)		(1,720	)

Loss before income tax expense		(4,892	)		(8,365	)		(6,290	)		(7,031	)		(26,578	)
Income tax expense		(2	)		—			—			—			(2	)
Net loss		(4,894	)		(8,365	)		(6,290	)		(7,031	)		(26,580	)
Weighted average shares outstanding, basic and diluted		18,792,850			20,123,041			20,265,020			21,956,993			20,293,100
Basic and diluted net loss per share	$	(0.26	)	$	(0.42	)	$	(0.31	)	$	(0.32	)	$	(1.31	)

	Three months ended
	March 31,			June 30,			September 30,			December 31,			Total for year
	2016			2016			2016			2016			2016

Operating expenses
Operations and development costs		883			1,309			1,887			2,269			6,348
General and administrative expense		1,295			1,516			1,434			2,365			6,610
Total operating expenses		2,178			2,825			3,321			4,634			12,958

Loss from operations		(2,178	)		(2,825	)		(3,321	)		(4,634	)		(12,958	)

Other income and expense

Interest expense		(2	)		(112	)		(203	)		(322	)		(639	)
Interest and other income		7			6			7			21			41

Total other expense, net		5			(106	)		(196	)		(301	)		(598	)

Loss before income tax expense		(2,173	)		(2,931	)		(3,517	)		(4,935	)		(13,556	)

Income tax expense		(1	)		—			—			—			(1	)

Net loss		(2,174	)		(2,931	)		(3,517	)		(4,935	)		(13,557	)

Weighted average shares outstanding, basic and diluted		14,137,442			14,735,077			15,574,620			16,603,725			15,267,233

Basic and diluted net loss per share	$	(0.15	)	$	(0.20	)	$	(0.23	)	$	(0.30	)	$	(0.89	)