| Schedule of quarterly results |
Unaudited Quarterly Results of Operations
(in thousands, except share and per share amounts)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
Three months ended |
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|
|
|
March 31,
2018 |
|
June 30,
2018 |
|
September 30,
2018 |
|
December 31,
2018 |
|
Total for year
2018 |
|
|
|
|
|
|
|
|
|
|
|
Revenue - sales |
|
$ |
1,726 |
|
|
$ |
483 |
|
|
$ |
1,169 |
|
|
$ |
1,071 |
|
|
$ |
4,449 |
|
|
|
|
|
|
|
|
|
|
|
|
Operating expenses |
|
|
|
|
|
|
|
|
|
|
Cost of product sales |
|
5,436 |
|
|
4,600 |
|
|
6,453 |
|
|
6,272 |
|
|
22,761 |
|
Research and development cost |
|
1,475 |
|
|
1,203 |
|
|
967 |
|
|
857 |
|
|
4,502 |
|
General and administrative expense |
|
1,775 |
|
|
3,913 |
|
|
2,174 |
|
|
6,352 |
|
|
14,214 |
|
Total operating expenses |
|
8,686 |
|
|
9,716 |
|
|
9,594 |
|
|
13,481 |
|
|
41,477 |
|
Loss from operations |
|
(6,960 |
) |
|
(9,233 |
) |
|
(8,425 |
) |
|
(12,410 |
) |
|
(37,028 |
) |
Other income and expense |
|
|
|
|
|
|
|
|
|
|
Interest expense |
|
(587 |
) |
|
(719 |
) |
|
(919 |
) |
|
(1,222 |
) |
|
(3,447 |
) |
Interest and other income |
|
17 |
|
|
25 |
|
|
81 |
|
|
100 |
|
|
223 |
|
Total other expense, net |
|
(570 |
) |
|
(694 |
) |
|
(838 |
) |
|
(1,122 |
) |
|
(3,224 |
) |
|
|
|
|
|
|
|
|
|
|
|
Loss before income tax expense |
|
(7,530 |
) |
|
(9,927 |
) |
|
(9,263 |
) |
|
(13,532 |
) |
|
(40,252 |
) |
Income tax expense |
|
(2 |
) |
|
— |
|
|
— |
|
|
— |
|
|
(2 |
) |
Net loss |
|
(7,532 |
) |
|
(9,927 |
) |
|
(9,263 |
) |
|
(13,532 |
) |
|
(40,254 |
) |
Weighted average shares outstanding, basic and diluted |
|
27,768,008 |
|
|
30,134,995 |
|
|
38,779,710 |
|
|
38,905,282 |
|
|
34,154,826 |
|
Basic and diluted net loss per share |
|
$ |
(0.27 |
) |
|
$ |
(0.33 |
) |
|
$ |
(0.24 |
) |
|
$ |
(0.35 |
) |
|
$ |
(1.18 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
|
|
March 31,
2017 |
|
June 30,
2017 |
|
September 30,
2017 |
|
December 31,
2017 |
|
Total for year
2017 |
|
|
|
|
|
|
|
|
|
|
|
Revenue - sales |
|
— |
|
|
603 |
|
|
589 |
|
|
896 |
|
|
2,088 |
|
|
|
|
|
|
|
|
|
|
|
|
Operating expenses |
|
|
|
|
|
|
|
|
|
|
Cost of product sales |
|
— |
|
|
2,531 |
|
|
3,140 |
|
|
3,870 |
|
|
9,541 |
|
Research and development cost |
|
2,987 |
|
|
2,184 |
|
|
1,367 |
|
|
1,565 |
|
|
8,103 |
|
General and administrative expense |
|
1,528 |
|
|
1,444 |
|
|
1,925 |
|
|
1,994 |
|
|
6,891 |
|
Impairment charge |
|
|
|
2,411 |
|
|
— |
|
|
— |
|
|
2,411 |
|
Total operating expenses |
|
4,515 |
|
|
8,570 |
|
|
6,432 |
|
|
7,429 |
|
|
26,946 |
|
Loss from operations |
|
(4,515 |
) |
|
(7,967 |
) |
|
(5,843 |
) |
|
(6,533 |
) |
|
(24,858 |
) |
Other income and expense |
|
|
|
|
|
|
|
|
|
|
Interest expense |
|
(388 |
) |
|
(408 |
) |
|
(454 |
) |
|
(511 |
) |
|
(1,761 |
) |
Interest and other income |
|
11 |
|
|
10 |
|
|
7 |
|
|
13 |
|
|
41 |
|
Total other expense, net |
|
(377 |
) |
|
(398 |
) |
|
(447 |
) |
|
(498 |
) |
|
(1,720 |
) |
|
|
|
|
|
|
|
|
|
|
|
Loss before income tax expense |
|
(4,892 |
) |
|
(8,365 |
) |
|
(6,290 |
) |
|
(7,031 |
) |
|
(26,578 |
) |
Income tax expense |
|
(2 |
) |
|
— |
|
|
— |
|
|
— |
|
|
(2 |
) |
Net loss |
|
(4,894 |
) |
|
(8,365 |
) |
|
(6,290 |
) |
|
(7,031 |
) |
|
(26,580 |
) |
Weighted average shares outstanding, basic and diluted |
|
18,792,850 |
|
|
20,123,041 |
|
|
20,265,020 |
|
|
21,956,993 |
|
|
20,293,100 |
|
Basic and diluted net loss per share |
|
(0.26 |
) |
|
(0.42 |
) |
|
(0.31 |
) |
|
(0.32 |
) |
|
(1.31 |
) |
|